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Figure 1: The typical drug development and approval process
- Uploaded by: U.S. Government Accountability Office
- License: United States Government Work
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- Date uploaded: 2020-02-03
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, gao20215sp, artificialintelligenceinhealthcare, ai, artificialintelligence, fda, foodanddrugadministration, hipaa, healthinsuranceportabilityandaccountabilityactof1996, ind, investigationalnewdrugapplication, melloddy, machinelearningledgerorchestrationfordrugdiscovery, mlpds, machinelearningforpharmaceuticaldiscoveryandsynthesisconsortium, nda, newdrugapplication, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, rd, researchanddevelopment, nationalacademyofmedicine, nam, technologyassessment
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Figure 2: The lock and key analogy for drug-target interactions
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- License: United States Government Work
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- 16,162 views
- Date uploaded: 2020-02-03
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, gao20215sp, artificialintelligenceinhealthcare, ai, artificialintelligence, fda, foodanddrugadministration, hipaa, healthinsuranceportabilityandaccountabilityactof1996, ind, investigationalnewdrugapplication, melloddy, machinelearningledgerorchestrationfordrugdiscovery, mlpds, machinelearningforpharmaceuticaldiscoveryandsynthesisconsortium, nda, newdrugapplication, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, rd, researchanddevelopment, nationalacademyofmedicine, nam, technologyassessment
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Figure 4: Machine learning could accelerate drug development
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- License: United States Government Work
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- 13,504 views
- Date uploaded: 2020-02-03
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, gao20215sp, artificialintelligenceinhealthcare, ai, artificialintelligence, fda, foodanddrugadministration, hipaa, healthinsuranceportabilityandaccountabilityactof1996, ind, investigationalnewdrugapplication, melloddy, machinelearningledgerorchestrationfordrugdiscovery, mlpds, machinelearningforpharmaceuticaldiscoveryandsynthesisconsortium, nda, newdrugapplication, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, rd, researchanddevelopment, nationalacademyofmedicine, nam, technologyassessment
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Figure 5: Challenges hindering the use of machine learning in drug development
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- License: United States Government Work
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- 10,625 views
- Date uploaded: 2020-02-03
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, gao20215sp, artificialintelligenceinhealthcare, ai, artificialintelligence, fda, foodanddrugadministration, hipaa, healthinsuranceportabilityandaccountabilityactof1996, ind, investigationalnewdrugapplication, melloddy, machinelearningledgerorchestrationfordrugdiscovery, mlpds, machinelearningforpharmaceuticaldiscoveryandsynthesisconsortium, nda, newdrugapplication, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, rd, researchanddevelopment, nationalacademyofmedicine, nam, technologyassessment
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Figure 1: The general design of a human organ-on-a-chip
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- License: United States Government Work
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- 5,062 views
- Date uploaded: 2025-06-18
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, humanorganonachip, gao25107335, 3d, threedimensional, darpa, defenseadvancedresearchprojectsagency, dod, departmentofdefense, epa, environmentalprotectionagency, fda, usfoodanddrugadministration, iccvam, interagencycoordinatingcommitteeonthevalidationofalternativemethods, iso, internationalorganizationforstandardization, istand, fdasinnovativescienceandtechnologyapproachesfornewdrugspilotprogram, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, nist, nationalinstituteofstandardsandtechnology, ooc, organonachip, oecd, organisationforeconomiccooperationanddevelopment, texval, texasamtissuechipvalidationconsortium
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Figure 3: The general steps and common time frame for drug development
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- License: United States Government Work
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- 5,039 views
- Date uploaded: 2025-06-18
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, humanorganonachip, gao25107335, 3d, threedimensional, darpa, defenseadvancedresearchprojectsagency, dod, departmentofdefense, epa, environmentalprotectionagency, fda, usfoodanddrugadministration, iccvam, interagencycoordinatingcommitteeonthevalidationofalternativemethods, iso, internationalorganizationforstandardization, istand, fdasinnovativescienceandtechnologyapproachesfornewdrugspilotprogram, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, nist, nationalinstituteofstandardsandtechnology, ooc, organonachip, oecd, organisationforeconomiccooperationanddevelopment, texval, texasamtissuechipvalidationconsortium
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Figure 5: Organ-on-a-chip (OOC) and drug development
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- License: United States Government Work
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- 5,029 views
- Date uploaded: 2025-06-18
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, humanorganonachip, gao25107335, 3d, threedimensional, darpa, defenseadvancedresearchprojectsagency, dod, departmentofdefense, epa, environmentalprotectionagency, fda, usfoodanddrugadministration, iccvam, interagencycoordinatingcommitteeonthevalidationofalternativemethods, iso, internationalorganizationforstandardization, istand, fdasinnovativescienceandtechnologyapproachesfornewdrugspilotprogram, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, nist, nationalinstituteofstandardsandtechnology, ooc, organonachip, oecd, organisationforeconomiccooperationanddevelopment, texval, texasamtissuechipvalidationconsortium
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Figure 6: Organ-on-a-chip (OOC) modeling multiple organ systems
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- License: United States Government Work
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- 5,014 views
- Date uploaded: 2025-06-18
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, humanorganonachip, gao25107335, 3d, threedimensional, darpa, defenseadvancedresearchprojectsagency, dod, departmentofdefense, epa, environmentalprotectionagency, fda, usfoodanddrugadministration, iccvam, interagencycoordinatingcommitteeonthevalidationofalternativemethods, iso, internationalorganizationforstandardization, istand, fdasinnovativescienceandtechnologyapproachesfornewdrugspilotprogram, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, nist, nationalinstituteofstandardsandtechnology, ooc, organonachip, oecd, organisationforeconomiccooperationanddevelopment, texval, texasamtissuechipvalidationconsortium
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State of Drug Development for Viral Families with High Potential to Cause Future Pandemics
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- License: United States Government Work
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- 1,111 views
- Date uploaded: 2023-10-04
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, antiviraldrugs, gao23105847, ai, artificialintelligence, app, antiviralprogramforpandemics, aspr, administrationforstrategicpreparednessandresponse, barda, biomedicaladvancedresearchanddevelopmentauthority, caresact, thecoronavirusaidreliefandeconomicsecurityact, cdc, centersfordiseasecontrolandprevention, covid19, coronavirusdisease2019, fda, foodanddrugadministration, hhs, departmentofhealthandhumanservices, ml, machinelearning, ncats, nationalcenterforadvancingtranslationalsciences, niaid, nationalinstituteofallergyandinfectiousdiseases, nih, nationalinstitutesofhealth, sarscov2, severeacuterespiratorysyndromecoronavirus2, who, worldhealthorganization
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Figure 1: An example of the SARS-CoV-2 viral life cycle
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- License: United States Government Work
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- 1,006 views
- Date uploaded: 2023-10-23
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, antiviraldrugs, gao23105847, ai, artificialintelligence, app, antiviralprogramforpandemics, aspr, administrationforstrategicpreparednessandresponse, barda, biomedicaladvancedresearchanddevelopmentauthority, caresact, thecoronavirusaidreliefandeconomicsecurityact, cdc, centersfordiseasecontrolandprevention, covid19, coronavirusdisease2019, fda, foodanddrugadministration, hhs, departmentofhealthandhumanservices, ml, machinelearning, ncats, nationalcenterforadvancingtranslationalsciences, niaid, nationalinstituteofallergyandinfectiousdiseases, nih, nationalinstitutesofhealth, sarscov2, severeacuterespiratorysyndromecoronavirus2, who, worldhealthorganization
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Figure 2: Virus-specific versus broad-spectrum antiviral drugs
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- 948 views
- Date uploaded: 2023-10-23
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, antiviraldrugs, gao23105847, ai, artificialintelligence, app, antiviralprogramforpandemics, aspr, administrationforstrategicpreparednessandresponse, barda, biomedicaladvancedresearchanddevelopmentauthority, caresact, thecoronavirusaidreliefandeconomicsecurityact, cdc, centersfordiseasecontrolandprevention, covid19, coronavirusdisease2019, fda, foodanddrugadministration, hhs, departmentofhealthandhumanservices, ml, machinelearning, ncats, nationalcenterforadvancingtranslationalsciences, niaid, nationalinstituteofallergyandinfectiousdiseases, nih, nationalinstitutesofhealth, sarscov2, severeacuterespiratorysyndromecoronavirus2, who, worldhealthorganization
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Figure 3: Advantages of Controlling a Diagnosed Disease versus Leaving a Disease Untreated
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- License: United States Government Work
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- 785 views
- Date uploaded: 2021-11-01
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, rarediseases, gao22104235, fda, foodanddrugadministration, gard, geneticandrarediseases, icd, internationalclassificationofdiseases, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, pppy, perpersonperyear, hhs, departmentofhealthandhumanservices
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Examples of Factors That May Interfere with Accurate Diagnosis
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- 779 views
- Date uploaded: 2021-11-01
- Tags: gao, governmentaccountabilityoffice, usgovernmentaccountabilityoffice, usgao, unitedstatesgovernmentaccountabilityoffice, government, congress, watchdog, oversight, governmentwatchdog, rarediseases, gao22104235, fda, foodanddrugadministration, gard, geneticandrarediseases, icd, internationalclassificationofdiseases, ncats, nationalcenterforadvancingtranslationalsciences, nih, nationalinstitutesofhealth, pppy, perpersonperyear, hhs, departmentofhealthandhumanservices
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